Scientists have found that areas of the brain associated with learning, memory, and emotion continue to produce new neurons in adulthood. This is in contrast to the old theory that the brain stops producing new neurons after adolescence. This discovery helps us to develop new methods of treating diseases of the nervous system, such as dementia. There are many new neurons in the hippocampus of the infant brain. However, whether the hippocampus in adults has always been a hot controversy, even if neurons are generated in adulthood, then it is also like mice and non-human spirits. As observed in long-earned animals, the rate of production slows with age. Although some studies have found new neurons in the hippocampus of the elderly, a study published in the "Nature" in March this year overturned this view. The study claims that in the late adolescence, new neurons in the hippocampus have fallen to undetectable levels. Now a study published by another team of scientists refuted this view. The new study found that the hippocampus in the adult brain always produces new neurons and does not decrease with age. This discovery can help us find ways to treat a variety of neurological diseases, such as Alzheimer's disease and other mental illnesses. The study was published on Cell Stem Cell on the 5th. Dr. Maura Boldrini of Columbia University is the first author of this article. She said: "Excitingly, neurons are produced throughout their lives. It seems that humans are indeed different from mice. The latter's neuron production rate will decline rapidly with age. Maybe humans need these new nerves. Yuan to achieve complex learning ability and cognitive behavioral responses to emotions." Boldrini and colleagues studied the hippocampus of 28 men and women aged 14 to 79 years. These brain samples were collected several hours after their death. Boldrini pointed out that what is important is that these samples were all healthy before their main life. This is different from many studies in the past. The research team used a variety of techniques to detect the degree of new blood vessels formed in the dentate gyrus at different ages and the number of cells. The dentate gyrus is an area in the hippocampus where new neurons are produced. Boldrini said: "According to mouse studies, these pluripotent stem cells usually don't do anything. They are static and then they can divide. Other studies show that when we were born, we had a limited number of such 'blast' cells. These 'blast' daughter cells divide the more cells into neurons by exponential division." The team found that in the anterior and middle regions of the dentate gyrus, the number of these 'parent cells' decreases with age. However, the number of cells produced by these mother cells did not decrease. Because the team found that no matter how old the dead were, there were tens of thousands of new, immature neurons in their dentate gyrus. Image Source: "Cell Stem Cell" Boldrini said: "Even if the number of 'master cells' is reduced, we can still generate enough neurons." However, the number of cells in the dentate gyrus that can produce neuroplasticity-related substances is reduced. Neuroplasticity refers to the ability of the brain to reconnect. Boldrini explained: "Although we can produce new neurons, their plasticity is reduced, and perhaps the established connections are reduced." Researchers point out that the decrease in plasticity can explain why healthy people are emotionally more vulnerable when they are old, but new cells, including neurons, can help combat cognitive and emotional decline. Image Source: "Cell Stem Cell" Boldrini said that what is important now is that we need to figure out what happened in the brains of people with Alzheimer's disease and other patients with emotional problems, because if there is a difference in the formation of new cells in the hippocampus of these people, it may be able to Help scientists find new therapeutic goals. Dr. Mercedes Paredes of the University of California, San Francisco, who is the author of another paper published last month, believes that adults will no longer produce new neurons. She was not convinced by the study. She said: “At the moment, I don’t think this new study can challenge our recent observations. If there is still neural formation in the hippocampus of the adult brain, it is an extremely rare phenomenon. We have taken additional steps to these suspicious The cells were extensively analyzed and the results showed that they are not new neurons." But Dr. Niels Haan of Cardiff University said that he believes that new neurons will be generated in the adult brain, although the function of these new neurons remains unclear. He said: "We learned from animal models that various learning and memory processes require neurons generated after adulthood. There is some evidence that there is a disorder in the nerves in the brain of people with mental disorders. The treatment is very meaningful." 5.08MM Power+ Signal Power Connector 2.54MM Pitch Signal Power Connector.Chip power connector is used in power module system. It can select the matching power + signal connector according to the need. The feature is that the number of power and signal contacts and the matching sequence can be selected arbitrarily while keeping the connector size and contact core number unchanged. 5.08MM Power+ Signal Power Connector ShenZhen Antenk Electronics Co,Ltd , https://www.antenkconn.com
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